BDBM50249284 2-(4-methyl-2-(2-(3-methyl-5-(trifluoromethyl)phenylamino)pyrimidin-4-yl)thiazol-5-yl)ethanol::CHEMBL475249
SMILES Cc1nc(sc1CCO)-c1ccnc(Nc2cc(C)cc(c2)C(F)(F)F)n1
InChI Key InChIKey=ITMOBXZLVLXOOL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50249284
Affinity DataKi: 22nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: >2.50E+3nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 3.50E+3nMAssay Description:Inhibition of ZAP70 (unknown origin)More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 3.50E+3nMAssay Description:Inhibition of SRC (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant Syk (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of SYK (unknown origin)-mediated FCepsilonRI signaling activity by mast cell degranulation assayMore data for this Ligand-Target Pair