BDBM50249298 BEVYXXA::CHEMBL512351::N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbamimidoyl)benzamido)-5-methoxybenzamide::betrixaban

SMILES: COc1ccc(NC(=O)c2ccc(cc2)C(=N)N(C)C)c(c1)C(=O)Nc1ccc(Cl)cn1

InChI Key: InChIKey=XHOLNRLADUSQLD-UHFFFAOYSA-N

Data: 3 KI  12 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50249298   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prothrombin (Human)	BDBM50249298 (N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Coagulation factor X (Human)	BDBM50249298 (N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
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Coagulation factor X (Human)	BDBM50249298 (N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
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Prothrombin (Human)	BDBM50249298 (N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
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Coagulation factor X (Human)	BDBM50249298 (N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50249298 (N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Prothrombin (Human)	BDBM50249298 (N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tissue-type plasminogen activator (Human)	BDBM50249298 (N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Vitamin K-dependent protein C (Human)	BDBM50249298 (N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Plasminogen (Human)	BDBM50249298 (N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50249298 (N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prothrombin (Human)	BDBM50249298 (N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Coagulation factor X (Human)	BDBM50249298 (N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbami...) Show SMILES Show InChI	GoogleScholar	UniChem		0.117	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Coagulation factor X (Human)	BDBM50249298 (N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbami...) Show SMILES Show InChI	GoogleScholar	UniChem		0.120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50249298 (N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbami...) Show SMILES Show InChI	GoogleScholar	UniChem		1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair