BDBM50249318 2-(2-(2-(3,5-dimethylphenylamino)pyrimidin-4-yl)-4-methylthiazol-5-yl)ethanol::CHEMBL471727
SMILES Cc1nc(sc1CCO)-c1ccnc(Nc2cc(C)cc(C)c2)n1
InChI Key InChIKey=QIYHYLDEYCTUSQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50249318
Affinity DataKi: 32nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 560nMAssay Description:Inhibition of ZAP70 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: >2.27E+3nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 3.50E+3nMAssay Description:Inhibition of SRC (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of SYK (unknown origin)-mediated FCepsilonRI signaling activity by mast cell degranulation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant Syk (unknown origin)More data for this Ligand-Target Pair