BDBM50249406 1-(3-tert-butyl-1-methyl-1H-pyrazol-5-yl)-3-(4-(pyridin-4-yloxy)phenyl)urea::CHEMBL472620::US9187470, 61

SMILES: CC(C)(C)c1cc(n(n1)C)NC(=O)Nc2ccc(cc2)Oc3ccncc3

InChI Key: InChIKey=MHSLDASSAFCCDO-UHFFFAOYSA-N

Data: 3 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50249406   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 13 (Human)	BDBM50249406 (1-(3-tert-butyl-1-methyl-1H-pyrazol-5-yl)-3-(4-(py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	620	n/a	n/a	n/a	n/a	n/a	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 13 (Human)	BDBM50249406 (1-(3-tert-butyl-1-methyl-1H-pyrazol-5-yl)-3-(4-(py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	82.7	n/a	n/a	n/a	n/a	n/a	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase (Human)	BDBM50249406 (1-(3-tert-butyl-1-methyl-1H-pyrazol-5-yl)-3-(4-(py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair