BDBM50249425 (4-(1H-benzo[d]imidazol-2-yl)piperidin-1-yl)(4-(piperidin-1-yl)phenyl)methanone::CHEMBL474839

SMILES O=C(N1CCC(CC1)c1nc2ccccc2[nH]1)c1ccc(cc1)N1CCCCC1

InChI Key InChIKey=QUCIVEDNOCKEPN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50249425   

Target5-hydroxytryptamine receptor 2B(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50249425((4-(1H-benzo[d]imidazol-2-yl)piperidin-1-yl)(4-(pi...)
Affinity DataIC50: 48nMAssay Description:Antagonist activity at 5-HT2B receptor expressed in CHOK1 cells assessed as inhibition of serotonin-induced intracellular Ca2+ flux by aequorin lumin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50249425((4-(1H-benzo[d]imidazol-2-yl)piperidin-1-yl)(4-(pi...)
Affinity DataIC50: 1.20E+4nMAssay Description:Antagonist activity at 5-HT2B receptor expressed in CHOK1 cells assessed as inhibition of serotonin-induced intracellular Ca2+ flux by aequorin lumin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed