BDBM50249453 2-(2,5-difluorobenzyl)-4-(5-methyl-1H-pyrazol-3-ylamino)phthalazin-1(2H)-one::CHEMBL516231

SMILES Cc1cc(Nc2nn(Cc3cc(F)ccc3F)c(=O)c3ccccc23)[nH]n1

InChI Key InChIKey=SVTBFGDAWVMFBQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50249453   

TargetAurora kinase B(Homo sapiens (Human))
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50249453(2-(2,5-difluorobenzyl)-4-(5-methyl-1H-pyrazol-3-yl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Aurora B by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50249453(2-(2,5-difluorobenzyl)-4-(5-methyl-1H-pyrazol-3-yl...)
Affinity DataIC50:  25nMAssay Description:Inhibition of Aurora A by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50249453(2-(2,5-difluorobenzyl)-4-(5-methyl-1H-pyrazol-3-yl...)
Affinity DataIC50:  2.29E+4nMAssay Description:Inhibition of recombinant Syk (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed