BDBM50249478 2-(2-aminoethylamino)-4-(phenylamino)pyrimidine-5-carboxamide::CHEMBL472590

SMILES NCCNc1ncc(C(N)=O)c(Nc2ccccc2)n1

InChI Key InChIKey=MJRLHEORMJRXGM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50249478   

TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Gvk Biosciences

Curated by ChEMBL
LigandPNGBDBM50249478(2-(2-aminoethylamino)-4-(phenylamino)pyrimidine-5-...)
Affinity DataIC50:  1.32E+4nMAssay Description:Inhibition of human GST-fused ZAP-70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50249478(2-(2-aminoethylamino)-4-(phenylamino)pyrimidine-5-...)
Affinity DataIC50:  280nMAssay Description:Inhibition of recombinant Syk (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed