BDBM50249877 (S)-2-(4-(4-(2-amino-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-6-yl)butyl)benzamido)pentanedioic acid::CHEMBL491104::N-{4-[4-(2-Amino-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-6-yl)-butyl]benzoyl}-L-glutamic Acid

SMILES: Nc1nc2sc(CCCCc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)cc2c(=O)[nH]1

InChI Key: InChIKey=KVBZUTNKUVNMNN-UHFFFAOYSA-N

Data: 1 KI  8 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50249877   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reduced folate transporter (Human)	BDBM50249877 ((S)-2-(4-(4-(2-amino-4-oxo-3,4-dihydrothieno[2,3-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Folate receptor alpha (Human)	BDBM50249877 ((S)-2-(4-(4-(2-amino-4-oxo-3,4-dihydrothieno[2,3-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
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Folate receptor beta (Human)	BDBM50249877 ((S)-2-(4-(4-(2-amino-4-oxo-3,4-dihydrothieno[2,3-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
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Proton-coupled folate transporter (Human)	BDBM50249877 ((S)-2-(4-(4-(2-amino-4-oxo-3,4-dihydrothieno[2,3-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Trifunctional purine biosynthetic protein adenosine-3 (Mouse)	BDBM50249877 ((S)-2-(4-(4-(2-amino-4-oxo-3,4-dihydrothieno[2,3-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Trifunctional purine biosynthetic protein adenosine-3 (Human)	BDBM50249877 ((S)-2-(4-(4-(2-amino-4-oxo-3,4-dihydrothieno[2,3-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
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Trifunctional purine biosynthetic protein adenosine-3 (Mouse)	BDBM50249877 ((S)-2-(4-(4-(2-amino-4-oxo-3,4-dihydrothieno[2,3-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.51E+6	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Trifunctional purine biosynthetic protein adenosine-3 (Human)	BDBM50249877 ((S)-2-(4-(4-(2-amino-4-oxo-3,4-dihydrothieno[2,3-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.33E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional purine biosynthesis protein ATIC (Human)	BDBM50249877 ((S)-2-(4-(4-(2-amino-4-oxo-3,4-dihydrothieno[2,3-d...) Show SMILES Show InChI	GoogleScholar	UniChem		9.48E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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