BDBM50249959 CHEMBL522428::[2-(Hydroxymethyl)-4-(methylethylidene)-5-oxo-2-2,3-dihydrofuryl]methyl 4-[2-(4-Methylphenyl)ethynyl]benzoate

SMILES [#6]\[#6](-[#6])=[#6]-1/[#6]C([#6]-[#8])([#6]-[#8]-[#6](=O)-c2ccc(cc2)C#Cc2ccc(-[#6])cc2)[#8]-[#6]-1=O

InChI Key InChIKey=PGBOLFMQGRFIRL-UHFFFAOYSA-N

Data  10 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50249959   

TargetProtein kinase C delta type(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50249959(CHEMBL522428 | [2-(Hydroxymethyl)-4-(methylethylid...)
Affinity DataKi:  2.70nMAssay Description:Displacement of [3H]PDBu form human PKCdelta in presence of plasma membrane lipid mimetic mixtureMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50249959(CHEMBL522428 | [2-(Hydroxymethyl)-4-(methylethylid...)
Affinity DataKi:  4.10nMAssay Description:Displacement of [3H]PDBu form human PKCbeta in presence of phosphatidylserineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50249959(CHEMBL522428 | [2-(Hydroxymethyl)-4-(methylethylid...)
Affinity DataKi:  5.40nMAssay Description:Displacement of [3H]PDBu form human PKCdelta in presence of phosphatidylserineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50249959(CHEMBL522428 | [2-(Hydroxymethyl)-4-(methylethylid...)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]PDBu form human PKCalpha in presence of phosphatidylserineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C gamma type(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50249959(CHEMBL522428 | [2-(Hydroxymethyl)-4-(methylethylid...)
Affinity DataKi:  6.20nMAssay Description:Displacement of [3H]PDBu form human PKCgamma in presence of phosphatidylserineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50249959(CHEMBL522428 | [2-(Hydroxymethyl)-4-(methylethylid...)
Affinity DataKi:  8.30nMAssay Description:Displacement of [3H]PDBu form human PKCepsilon in presence of plasma membrane lipid mimetic mixtureMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50249959(CHEMBL522428 | [2-(Hydroxymethyl)-4-(methylethylid...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]PDBu form human PKCepsilon in presence of phosphatidylserineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50249959(CHEMBL522428 | [2-(Hydroxymethyl)-4-(methylethylid...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]PDBu form human PKCbeta in presence of plasma membrane lipid mimetic mixtureMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50249959(CHEMBL522428 | [2-(Hydroxymethyl)-4-(methylethylid...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]PDBu form human PKCalpha in presence of plasma membrane lipid mimetic mixtureMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C gamma type(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50249959(CHEMBL522428 | [2-(Hydroxymethyl)-4-(methylethylid...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]PDBu form human PKCgamma in presence of plasma membrane lipid mimetic mixtureMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed