BDBM50250101 (S)-7-(Biphenyl-3-ylamino)-7-oxo-6-(thiazole-5-carbonylamino)heptylboronic acid::CHEMBL492097

SMILES OB(O)CCCCC[C@H](NC(=O)c1cncs1)C(=O)Nc1cccc(c1)-c1ccccc1

InChI Key InChIKey=KWEAONYBPFXGPU-FQEVSTJZSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50250101   

TargetHistone deacetylase 1(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50250101((S)-7-(Biphenyl-3-ylamino)-7-oxo-6-(thiazole-5-car...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of human recombinant HDAC1 by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50250101((S)-7-(Biphenyl-3-ylamino)-7-oxo-6-(thiazole-5-car...)
Affinity DataIC50:  110nMAssay Description:Inhibition of human recombinant HDAC6 by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50250101((S)-7-(Biphenyl-3-ylamino)-7-oxo-6-(thiazole-5-car...)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibition of human recombinant HDAC8 by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50250101((S)-7-(Biphenyl-3-ylamino)-7-oxo-6-(thiazole-5-car...)
Affinity DataIC50:  530nMAssay Description:Inhibition of human recombinant HDAC2 by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed