BDBM50250106 CHEMBL4103560

SMILES OCCNC(=O)c1cnn2c(O)cc(nc12)-c1ccccc1

InChI Key InChIKey=PKCQPXUFOPVMKX-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50250106   

TargetCyclic GMP-AMP synthase(Homo sapiens)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50250106(CHEMBL4103560)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of human cGAS (2 to 522 residues) expressed in Sf9 insect cells assessed as reduction in cGAMP level using ISD DNA as substrate in presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclic GMP-AMP synthase(Homo sapiens)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50250106(CHEMBL4103560)
Affinity DataKd:  1.25E+4nMAssay Description:Binding affinity to human cGAS (2 to 522 residues) expressed in Sf9 insect cells by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclic GMP-AMP synthase(Homo sapiens)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50250106(CHEMBL4103560)
Affinity DataIC50:  1.51E+4nMAssay Description:Inhibition of human cGAS (2 to 522 residues) expressed in Sf9 insect cells assessed as reduction in cGAMP level using ISD DNA as substrate in presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed