BDBM50250931 CHEMBL4079092
SMILES Cc1ncnc2ccc(Nc3nn(cc3C(N)=O)[C@H]3COCC[C@@H]3C#N)cc12
InChI Key InChIKey=PGBIJJZJAXIUDR-PXAZEXFGSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50250931
Affinity DataIC50: 783nMAssay Description:Inhibition of GST-tagged recombinant human JAK3 catalytic domain expressed in baculovirus expression system using LCB-EQEDEPEGDYFEWLW-NH2 as substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 1.64E+3nMAssay Description:Inhibition of JAK2 in EPO-stimulated human TF1 cells expressing stably integrated beta-lactamase reporter gene under control of STAT5 response elemen...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of GST-tagged recombinant human JAK2 catalytic domain expressed in baculovirus expression system using LCB-EQEDEPEGDYFEWLW-NH2 as substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human TYK2 catalytic domain expressed in baculovirus expression system using LCB-EQEDEPEGDYFEWLW-NH2 ...More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of JAK2 in EPO-stimulated human TF1 cells expressing stably integrated beta-lactamase reporter gene under control of STAT5 response elemen...More data for this Ligand-Target Pair
Affinity DataIC50: 0.160nMAssay Description:Inhibition of GST-tagged recombinant human JAK1 catalytic domain expressed in baculovirus expression system using LCB-EQEDEPEGDYFEWLW-NH2 as substrat...More data for this Ligand-Target Pair