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BDBM50251610 CHEMBL518154::N,1-dimethyl-N-(6-(2-methylpyridin-3-yloxy)pyridin-3-yl)-1H-indole-3-carboxamide

SMILES: CN(C(=O)c1cn(C)c2ccccc12)c1ccc(Oc2cccnc2C)nc1

InChI Key: InChIKey=JMWLXQZFTDZDLO-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50251610   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))
BDBM50251610
PNG
(CHEMBL518154 | N,1-dimethyl-N-(6-(2-methylpyridin-...)
Show SMILES CN(C(=O)c1cn(C)c2ccccc12)c1ccc(Oc2cccnc2C)nc1
Show InChI InChI=1S/C22H20N4O2/c1-15-20(9-6-12-23-15)28-21-11-10-16(13-24-21)26(3)22(27)18-14-25(2)19-8-5-4-7-17(18)19/h4-14H,1-3H3
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Article
PubMed
n/an/a 6.37E+3n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Displacement of [3H]mesulergine at human cloned 5HT2C receptor expressed in CHOK1 cell


Bioorg Med Chem Lett 18: 3844-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.064
BindingDB Entry DOI: 10.7270/Q2P84BQN
More data for this
Ligand-Target Pair