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BDBM50251690 6-(2-chlorophenylsulfonyl)-1,2,3,4,5,6-hexahydroazepino[4,5-b]indole::CHEMBL471099

SMILES: Clc1ccccc1S(=O)(=O)n1c2CCNCCc2c2ccccc12

InChI Key: InChIKey=KWHMREXWEQGZAI-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50251690   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))
BDBM50251690
PNG
(6-(2-chlorophenylsulfonyl)-1,2,3,4,5,6-hexahydroaz...)
Show SMILES Clc1ccccc1S(=O)(=O)n1c2CCNCCc2c2ccccc12
Show InChI InChI=1S/C18H17ClN2O2S/c19-15-6-2-4-8-18(15)24(22,23)21-16-7-3-1-5-13(16)14-9-11-20-12-10-17(14)21/h1-8,20H,9-12H2
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Similars

Article
PubMed
19n/an/an/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cells


Bioorg Med Chem Lett 18: 3929-31 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.030
BindingDB Entry DOI: 10.7270/Q2959HCP
More data for this
Ligand-Target Pair