BDBM50251720 CHEMBL480154::ethyl 4-((1S,5R,6s)-6-(2-((2S,4S)-2-cyano-4-fluoropyrrolidin-1-yl)-2-oxoethylamino)-3-aza-bicyclo[3.1.0]hexan-3-yl)benzoate

SMILES CCOC(=O)c1ccc(cc1)N1C[C@H]2[C@@H](C1)[C@@H]2NCC(=O)N1C[C@@H](F)C[C@H]1C#N

InChI Key InChIKey=KTNUSPOEGQOANN-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50251720   

TargetDipeptidyl peptidase 4(Human)
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50251720(ethyl 4-((1S,5R,6s)-6-(2-((2S,4S)-2-cyano-4-fluoro...)
Affinity DataIC50: 229nMAssay Description:Inhibition of human plasma DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50251720(ethyl 4-((1S,5R,6s)-6-(2-((2S,4S)-2-cyano-4-fluoro...)
Affinity DataIC50: 640nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50251720(ethyl 4-((1S,5R,6s)-6-(2-((2S,4S)-2-cyano-4-fluoro...)
Affinity DataIC50: 2.08E+3nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50251720(ethyl 4-((1S,5R,6s)-6-(2-((2S,4S)-2-cyano-4-fluoro...)
Affinity DataIC50: 9.88E+3nMAssay Description:Inhibition of DPP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50251720(ethyl 4-((1S,5R,6s)-6-(2-((2S,4S)-2-cyano-4-fluoro...)
Affinity DataIC50: 6.22E+4nMAssay Description:Inhibition of PPCEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed