BDBM50252038 6-((4-(1-acetyl-1,2,3,6-tetrahydropyridin-4-yl)phenoxy)methyl)-7-(2-cyclohexylethyl)-7H-pyrrolo[2,3-d]pyrimidine-2-carbonitrile::CHEMBL479603

SMILES CC(=O)N1CCC(=CC1)c1ccc(OCc2cc3cnc(nc3n2CCC2CCCCC2)C#N)cc1

InChI Key InChIKey=ZPLGPMKFENTWRH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50252038   

TargetCathepsin S(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50252038(6-((4-(1-acetyl-1,2,3,6-tetrahydropyridin-4-yl)phe...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human recombinant cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50252038(6-((4-(1-acetyl-1,2,3,6-tetrahydropyridin-4-yl)phe...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human recombinant cathepsin L by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50252038(6-((4-(1-acetyl-1,2,3,6-tetrahydropyridin-4-yl)phe...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed