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BDBM50252336 CHEMBL4080127

SMILES: CCN(CC)CCCC(C)Nc1nc(CCc2ccc(cc2)C(F)(F)F)nc2ccc(N)cc12

InChI Key: InChIKey=IAPONCHPSBAUCE-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50252336   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Maternal embryonic leucine zipper kinase


(Homo sapiens (Human))
BDBM50252336
PNG
(CHEMBL4080127)
Show SMILES CCN(CC)CCCC(C)Nc1nc(CCc2ccc(cc2)C(F)(F)F)nc2ccc(N)cc12
Show InChI InChI=1/C26H34F3N5/c1-4-34(5-2)16-6-7-18(3)31-25-22-17-21(30)13-14-23(22)32-24(33-25)15-10-19-8-11-20(12-9-19)26(27,28)29/h8-9,11-14,17-18H,4-7,10,15-16,30H2,1-3H3,(H,31,32,33)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 1.30E+3n/an/an/an/an/an/a



Indiana University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of MELK (unknown origin)


Bioorg Med Chem 25: 2995-3005 (2017)

More data for this
Ligand-Target Pair