BDBM50252439 (2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methyl-1-{[3-(4H-1,2,4-triazol-4-yl)phenyl]sulfonyl}piperazine::CHEMBL480941

SMILES C[C@@H]1CN(CCN1S(=O)(=O)c1cccc(c1)-n1cnnc1)c1ccc(F)cc1C(F)(F)F

InChI Key InChIKey=HZRLXFQWJIMSCI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50252439   

Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50252439((2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-meth...)
Affinity DataIC50: 120nMAssay Description:Inhibition of C57BL/6 mouse 11betaHSD1 in presence of human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50252439((2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-meth...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human 11betaHSD1 expressed in CHO cells by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50252439((2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-meth...)
Affinity DataIC50: 230nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cells by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed