BindingDB PrimarySearch

BDBM50252513 3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-9-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::9-OH-risperidone::9-hydroxy risperidone::CHEMBL1621::Invega::PALIPERIDONE

SMILES: Cc1nc2C(O)CCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12

InChI Key: InChIKey=PMXMIIMHBWHSKN-UHFFFAOYSA-N

Data: 69 KI 14 IC50 1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 99 hits for monomerid = 50252513
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2A (Human)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
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Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S (Human)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.94E+5	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	8.30	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Human)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.29E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium channel protein type 5 subunit alpha (Human)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.51E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Voltage-dependent L-type calcium channel subunit alpha-1C (Human)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	3.98E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Voltage-dependent L-type calcium channel subunit alpha-1C (Human)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily D member 3 (Human)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	6.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily E/KQT member 1 (Human)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.51E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium channel protein type 5 subunit alpha (Human)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.58E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
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D(3) dopamine receptor (Human)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2A (Rat)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	0.220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2A (Rat)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	0.25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2A (Human)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	0.430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2A (Human)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	0.830	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(3) dopamine receptor (Human)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2A (Human)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2A (Human)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	1.21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 7 (Mouse)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2C adrenergic receptor (Human)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H1 receptor (Human)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Rat)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Rat)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2B adrenergic receptor (Human)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Rat)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Rat)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Rat)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	4.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Rat)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	6.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 7 (Human)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	6.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(3) dopamine receptor (Human)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	6.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1D (Human)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	7.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(3) dopamine receptor (Human)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	7.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(3) dopamine receptor (Rat)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	7.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2B adrenergic receptor (Human)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	9.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H1 receptor (Guinea pig)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Human)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	10.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Human)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2C adrenergic receptor (Human)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2A adrenergic receptor (Human)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1B (Human)	BDBM50252513 (9-OH-risperidone \| Invega \| CHEMBL1621 \| 9-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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