BDBM50252545 6-(4-chlorobenzyl)-7-(2-cyclooctylethyl)-7H-pyrrolo[2,3-d]pyrimidine-2-carbonitrile::CHEMBL522326

SMILES Clc1ccc(Cc2cc3cnc(nc3n2CCC2CCCCCCC2)C#N)cc1

InChI Key InChIKey=SKABQRUBNPTKTK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50252545   

TargetProcathepsin L(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50252545(6-(4-chlorobenzyl)-7-(2-cyclooctylethyl)-7H-pyrrol...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human recombinant cathepsin L by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50252545(6-(4-chlorobenzyl)-7-(2-cyclooctylethyl)-7H-pyrrol...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50252545(6-(4-chlorobenzyl)-7-(2-cyclooctylethyl)-7H-pyrrol...)
Affinity DataIC50:  99nMAssay Description:Inhibition of human recombinant cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed