BDBM50252653 7-(2-cyclohexylethyl)-6-((methyl(phenyl)amino)methyl)-7H-pyrrolo[2,3-d]pyrimidine-2-carbonitrile::CHEMBL493244

SMILES CN(Cc1cc2cnc(nc2n1CCC1CCCCC1)C#N)c1ccccc1

InChI Key InChIKey=AQIXEIGNFOLLPK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50252653   

TargetCathepsin S(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50252653(7-(2-cyclohexylethyl)-6-((methyl(phenyl)amino)meth...)
Affinity DataIC50:  52nMAssay Description:Inhibition of human recombinant cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50252653(7-(2-cyclohexylethyl)-6-((methyl(phenyl)amino)meth...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human recombinant cathepsin L by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50252653(7-(2-cyclohexylethyl)-6-((methyl(phenyl)amino)meth...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed