BDBM50252875 4-(Spiro[chromene-2,4'-piperidine]-4-yl)benzoic acid::CHEMBL494266

SMILES OC(=O)c1ccc(cc1)C1=CC2(CCNCC2)Oc2ccccc12

InChI Key InChIKey=QXAHOCVRJICIGL-UHFFFAOYSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50252875   

TargetDelta-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50252875(4-(Spiro[chromene-2,4'-piperidine]-4-yl)benzoic ac...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]diprenorphine from human delta opioid receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50252875(4-(Spiro[chromene-2,4'-piperidine]-4-yl)benzoic ac...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human ERG channel in HEK293 cells by voltage-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50252875(4-(Spiro[chromene-2,4'-piperidine]-4-yl)benzoic ac...)
Affinity DataEC50:  220nMAssay Description:Agonist activity at human delta opioid receptor in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed