BDBM50252921 (S)-1-(2'-Amino-2'-carboxyethyl)-6,6-dimethyl-2,3,4,5,6,7-hexahydrocyclopentapyrimidin-2,4-dione::CHEMBL492629

SMILES CC1(C)Cc2c(C1)c(=O)[nH]c(=O)n2C[C@H](N)C(O)=O

InChI Key InChIKey=UCJXLBUMFLKZEX-ZETCQYMHSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50252921   

TargetGlutamate receptor 1(Rattus norvegicus (Rat))
European Research Centre For Drug Discovery And Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50252921((S)-1-(2'-Amino-2'-carboxyethyl)-6,6-dimethyl-2,3,...)
Affinity DataKi:  102nMAssay Description:Displacement of (R,S)-[5-methyl-3H]AMPA from rat recombinant flop iGluR1 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Rattus norvegicus)
European Research Centre For Drug Discovery And Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50252921((S)-1-(2'-Amino-2'-carboxyethyl)-6,6-dimethyl-2,3,...)
Affinity DataKi:  126nMAssay Description:Displacement of (R,S)-[5-methyl-3H]AMPA from rat recombinant flop iGluR2(R) expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(RAT)
European Research Centre For Drug Discovery And Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50252921((S)-1-(2'-Amino-2'-carboxyethyl)-6,6-dimethyl-2,3,...)
Affinity DataKi:  976nMAssay Description:Displacement of [3H]SYM2081 from rat recombinant iGluR5(Q)1b expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 3(RAT)
European Research Centre For Drug Discovery And Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50252921((S)-1-(2'-Amino-2'-carboxyethyl)-6,6-dimethyl-2,3,...)
Affinity DataKi:  1.51E+3nMAssay Description:Displacement of (R,S)-[5-methyl-3H]AMPA from rat recombinant flop iGluR3 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Rattus norvegicus)
European Research Centre For Drug Discovery And Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50252921((S)-1-(2'-Amino-2'-carboxyethyl)-6,6-dimethyl-2,3,...)
Affinity DataKi:  1.59E+3nMAssay Description:Displacement of (R,S)-[5-methyl-3H]AMPA from rat recombinant flop iGluR4 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
European Research Centre For Drug Discovery And Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50252921((S)-1-(2'-Amino-2'-carboxyethyl)-6,6-dimethyl-2,3,...)
Affinity DataKi: >1.00E+6nMAssay Description:Displacement of [3H]kainic acid from rat recombinant iGluR6(V,C,R) receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed