BDBM50252940 4-[(Butyl{4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl}amino)methyl]-2,6-dichlorophenol::CHEMBL493241::GSK-9772
SMILES CCCCN(Cc1cc(Cl)c(O)c(Cl)c1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F
InChI Key InChIKey=TYYLMKBOWXDDCT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50252940
Affinity DataEC50: 3.00E+3nMAssay Description:Activation of LXRbeta (unknown origin) by GAL4 reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Displacement of [N-methyl-3H]GW0438 from human biotinylated LXRbeta ligand binding domainMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 250nMAssay Description:Inhibition of human PXRMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Displacement of [N-methyl-3H]GW0438 from human biotinylated LXRalpha ligand binding domainMore data for this Ligand-Target Pair
Affinity DataEC50: 3.00E+3nMAssay Description:Activation of LXRalpha (unknown origin) by GAL4 reporter gene assayMore data for this Ligand-Target Pair