BDBM50252940 4-[(Butyl{4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl}amino)methyl]-2,6-dichlorophenol::CHEMBL493241::GSK-9772

SMILES CCCCN(Cc1cc(Cl)c(O)c(Cl)c1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F

InChI Key InChIKey=TYYLMKBOWXDDCT-UHFFFAOYSA-N

Data  2 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50252940   

TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50252940(4-[(Butyl{4-[2,2,2-trifluoro-1-hydroxy-1-(trifluor...)
Affinity DataEC50:  3.00E+3nMAssay Description:Activation of LXRbeta (unknown origin) by GAL4 reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50252940(4-[(Butyl{4-[2,2,2-trifluoro-1-hydroxy-1-(trifluor...)
Affinity DataIC50:  30nMAssay Description:Displacement of [N-methyl-3H]GW0438 from human biotinylated LXRbeta ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50252940(4-[(Butyl{4-[2,2,2-trifluoro-1-hydroxy-1-(trifluor...)
Affinity DataEC50:  250nMAssay Description:Inhibition of human PXRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50252940(4-[(Butyl{4-[2,2,2-trifluoro-1-hydroxy-1-(trifluor...)
Affinity DataIC50:  180nMAssay Description:Displacement of [N-methyl-3H]GW0438 from human biotinylated LXRalpha ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50252940(4-[(Butyl{4-[2,2,2-trifluoro-1-hydroxy-1-(trifluor...)
Affinity DataEC50:  3.00E+3nMAssay Description:Activation of LXRalpha (unknown origin) by GAL4 reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed