BDBM50253208 CHEMBL492871::N-Benzyl-4-(2-diphenyl)-1-piperazinehexanamide

SMILES O=C(CCCCCN1CCN(CC1)c1ccccc1-c1ccccc1)NCc1ccccc1

InChI Key InChIKey=LQFAQQWXFSOOQJ-UHFFFAOYSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50253208   

Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50253208(CHEMBL492871 | N-Benzyl-4-(2-diphenyl)-1-piperazin...)
Affinity DataKi:  0.800nMAssay Description:Displacement of [3H]LSD from rat cloned 5HT7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50253208(CHEMBL492871 | N-Benzyl-4-(2-diphenyl)-1-piperazin...)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]-SB-26997 from human 5-HT7A receptor expressed in HEK293 cell membranes after 60 mins by microbeta counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50253208(CHEMBL492871 | N-Benzyl-4-(2-diphenyl)-1-piperazin...)
Affinity DataKi:  161nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50253208(CHEMBL492871 | N-Benzyl-4-(2-diphenyl)-1-piperazin...)
Affinity DataKi:  503nMAssay Description:Displacement of [3H]spiroperidol from human cloned dopamine D2L receptor expressed in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(GUINEA PIG)
Università

Curated by ChEMBL
LigandPNGBDBM50253208(CHEMBL492871 | N-Benzyl-4-(2-diphenyl)-1-piperazin...)
Affinity DataEC50:  4.50E+6nMAssay Description:Agonist activity at 5HT7 receptor assessed as relaxation of substance P-induced Dunkin-Hartley guinea pig ileum contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed