BDBM50253281 CHEMBL522691::N-(4-Cyanophenylmethyl)-4-(2-diphenyl)-1-piperazinehexanamide::US20240199555, Reference LP211

SMILES: O=C(CCCCCN1CCN(CC1)c1ccccc1-c1ccccc1)NCc1ccc(cc1)C#N

InChI Key: InChIKey=BQEDZLDNNBDKDS-UHFFFAOYSA-N

Data: 19 KI  1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 21 hits for monomerid = 50253281   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 7 (Human)	BDBM50253281 (N-(4-Cyanophenylmethyl)-4-(2-diphenyl)-1-piperazin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.160	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 7 (Guinea pig)	BDBM50253281 (N-(4-Cyanophenylmethyl)-4-(2-diphenyl)-1-piperazin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	600	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 7 (Human)	BDBM50253281 (N-(4-Cyanophenylmethyl)-4-(2-diphenyl)-1-piperazin...) Show SMILES Show InChI	GoogleScholar	UniChem		0.110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 7 (Human)	BDBM50253281 (N-(4-Cyanophenylmethyl)-4-(2-diphenyl)-1-piperazin...) Show SMILES Show InChI	GoogleScholar	UniChem		0.580	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 7 (Human)	BDBM50253281 (N-(4-Cyanophenylmethyl)-4-(2-diphenyl)-1-piperazin...) Show SMILES Show InChI	GoogleScholar	UniChem		0.580	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 7 (Rat)	BDBM50253281 (N-(4-Cyanophenylmethyl)-4-(2-diphenyl)-1-piperazin...) Show SMILES Show InChI	GoogleScholar	UniChem		0.580	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 7 (Rat)	BDBM50253281 (N-(4-Cyanophenylmethyl)-4-(2-diphenyl)-1-piperazin...) Show SMILES Show InChI	GoogleScholar	UniChem		0.580	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 7 (Rat)	BDBM50253281 (N-(4-Cyanophenylmethyl)-4-(2-diphenyl)-1-piperazin...) Show SMILES Show InChI	GoogleScholar	UniChem		0.580	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 7 (Human)	BDBM50253281 (N-(4-Cyanophenylmethyl)-4-(2-diphenyl)-1-piperazin...) Show SMILES Show InChI	GoogleScholar	UniChem		15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 7 (Human)	BDBM50253281 (N-(4-Cyanophenylmethyl)-4-(2-diphenyl)-1-piperazin...) Show SMILES Show InChI	GoogleScholar	UniChem		15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 7 (Human)	BDBM50253281 (N-(4-Cyanophenylmethyl)-4-(2-diphenyl)-1-piperazin...) Show SMILES Show InChI	GoogleScholar	UniChem		15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rat)	BDBM50253281 (N-(4-Cyanophenylmethyl)-4-(2-diphenyl)-1-piperazin...) Show SMILES Show InChI	GoogleScholar	UniChem		23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50253281 (N-(4-Cyanophenylmethyl)-4-(2-diphenyl)-1-piperazin...) Show SMILES Show InChI	GoogleScholar	UniChem		142	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Human)	BDBM50253281 (N-(4-Cyanophenylmethyl)-4-(2-diphenyl)-1-piperazin...) Show SMILES Show InChI	GoogleScholar	UniChem		188	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Human)	BDBM50253281 (N-(4-Cyanophenylmethyl)-4-(2-diphenyl)-1-piperazin...) Show SMILES Show InChI	GoogleScholar	UniChem		188	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Human)	BDBM50253281 (N-(4-Cyanophenylmethyl)-4-(2-diphenyl)-1-piperazin...) Show SMILES Show InChI	GoogleScholar	UniChem		188	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50253281 (N-(4-Cyanophenylmethyl)-4-(2-diphenyl)-1-piperazin...) Show SMILES Show InChI	GoogleScholar	UniChem		242	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Human)	BDBM50253281 (N-(4-Cyanophenylmethyl)-4-(2-diphenyl)-1-piperazin...) Show SMILES Show InChI	GoogleScholar	UniChem		379	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Human)	BDBM50253281 (N-(4-Cyanophenylmethyl)-4-(2-diphenyl)-1-piperazin...) Show SMILES Show InChI	GoogleScholar	UniChem		379	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 6 (Human)	BDBM50253281 (N-(4-Cyanophenylmethyl)-4-(2-diphenyl)-1-piperazin...) Show SMILES Show InChI	GoogleScholar	UniChem		1.57E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Sigma non-opioid intracellular receptor 1 (Human)	BDBM50253281 (N-(4-Cyanophenylmethyl)-4-(2-diphenyl)-1-piperazin...) Show SMILES Show InChI	GoogleScholar	UniChem		>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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