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BDBM50253547 3-Methoxy-5-[3-(4-methoxybenzyl)naphthalen-2-yl]pyridine::CHEMBL446775

SMILES: COc1ccc(Cc2cc3ccccc3cc2-c2cncc(OC)c2)cc1

InChI Key: InChIKey=QUWZZCOGVFPHNJ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50253547   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytochrome P450 11B1, mitochondrial


(Homo sapiens (Human))
BDBM50253547
PNG
(3-Methoxy-5-[3-(4-methoxybenzyl)naphthalen-2-yl]py...)
Show SMILES COc1ccc(Cc2cc3ccccc3cc2-c2cncc(OC)c2)cc1
Show InChI InChI=1S/C24H21NO2/c1-26-22-9-7-17(8-10-22)11-20-12-18-5-3-4-6-19(18)14-24(20)21-13-23(27-2)16-25-15-21/h3-10,12-16H,11H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.81E+3n/an/an/an/an/an/a



Saarland University

Curated by ChEMBL


Assay Description
Inhibition of human adrenal corticoid CYP11B1 expressed in chinese hamster V79 MZh cells


J Med Chem 51: 6138-49 (2008)


Article DOI: 10.1021/jm800683c
BindingDB Entry DOI: 10.7270/Q22J6BP4
More data for this
Ligand-Target Pair
Cytochrome P450 11B2 (CYP11B2)


(Homo sapiens (Human))
BDBM50253547
PNG
(3-Methoxy-5-[3-(4-methoxybenzyl)naphthalen-2-yl]py...)
Show SMILES COc1ccc(Cc2cc3ccccc3cc2-c2cncc(OC)c2)cc1
Show InChI InChI=1S/C24H21NO2/c1-26-22-9-7-17(8-10-22)11-20-12-18-5-3-4-6-19(18)14-24(20)21-13-23(27-2)16-25-15-21/h3-10,12-16H,11H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 7.70n/an/an/an/an/an/a



Saarland University

Curated by ChEMBL


Assay Description
Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cells


J Med Chem 51: 6138-49 (2008)


Article DOI: 10.1021/jm800683c
BindingDB Entry DOI: 10.7270/Q22J6BP4
More data for this
Ligand-Target Pair