BDBM50253733 2-{4-[2-Acetylamino-3-(4-fluoro-phenyl)-propionyl]-2-oxo-3-propyl-piperazin-1-yl}-N-methyl-3-naphthalen-2-yl-propionamide::CHEMBL466380

SMILES CCC[C@@H]1N(CCN([C@@H](Cc2ccc3ccccc3c2)C(=O)NC)C1=O)C(=O)[C@@H](Cc1ccc(F)cc1)NC(C)=O

InChI Key InChIKey=HJSDVHQHZYTQEH-ULNSLHSMSA-N

Data  3 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50253733   

TargetMelanocortin receptor 4(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50253733(2-{4-[2-Acetylamino-3-(4-fluoro-phenyl)-propionyl]...)
Affinity DataKi:  8nMAssay Description:Displacement of europium-labeled NDP-alpha-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50253733(2-{4-[2-Acetylamino-3-(4-fluoro-phenyl)-propionyl]...)
Affinity DataKi:  201nMAssay Description:Displacement of europium-labeled NDP-alpha-MSH from human MC3R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50253733(2-{4-[2-Acetylamino-3-(4-fluoro-phenyl)-propionyl]...)
Affinity DataKi:  1.39E+3nMAssay Description:Agonist activity at human MC1R expressed in HEK293 cells assessed as effect on CRE-driven luminescence by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50253733(2-{4-[2-Acetylamino-3-(4-fluoro-phenyl)-propionyl]...)
Affinity DataEC50:  3nMAssay Description:Agonist activity at human MC4R expressed in HEK293 cells assessed as effect on CRE-driven luminescence by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50253733(2-{4-[2-Acetylamino-3-(4-fluoro-phenyl)-propionyl]...)
Affinity DataEC50:  1.08E+3nMAssay Description:Agonist activity at human MC1R expressed in HEK293 cells assessed as effect on CRE-driven luminescence by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50253733(2-{4-[2-Acetylamino-3-(4-fluoro-phenyl)-propionyl]...)
Affinity DataEC50:  113nMAssay Description:Agonist activity at human MC3R expressed in HEK293 cells assessed as effect on CRE-driven luminescence by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed