BDBM50253810 CHEMBL459505::N-(4-(2-ethyl-1-(1H-1,2,4-triazol-1-yl)butyl)phenyl)benzo[d]thiazol-2-amine::R-115866::R115866::US9963439, Talarozole

SMILES: CCC(CC)C(c1ccc(Nc2nc3ccccc3s2)cc1)n1cncn1

InChI Key: InChIKey=SNFYYXUGUBUECJ-UHFFFAOYSA-N

Data: 7 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50253810   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 26A1 (Human)	BDBM50253810 (R115866 | CHEMBL459505 | N-(4-(2-ethyl-1-(1H-1,2,4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 26B1 (Human)	BDBM50253810 (R115866 | CHEMBL459505 | N-(4-(2-ethyl-1-(1H-1,2,4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.460	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C8 (Human)	BDBM50253810 (R115866 | CHEMBL459505 | N-(4-(2-ethyl-1-(1H-1,2,4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50253810 (R115866 | CHEMBL459505 | N-(4-(2-ethyl-1-(1H-1,2,4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	680	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50253810 (R115866 | CHEMBL459505 | N-(4-(2-ethyl-1-(1H-1,2,4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 26A1 (Human)	BDBM50253810 (R115866 | CHEMBL459505 | N-(4-(2-ethyl-1-(1H-1,2,4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Cytochrome P450 26A1 (Human)	BDBM50253810 (R115866 | CHEMBL459505 | N-(4-(2-ethyl-1-(1H-1,2,4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Human)	BDBM50253810 (R115866 | CHEMBL459505 | N-(4-(2-ethyl-1-(1H-1,2,4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.460	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair