BDBM50253982 CHEMBL461194::N-(2-hydroxyethyl)-3-(2,3,4-trichlorophenyl)-1H-pyrazole-5-carboxamide::cid_24178170

SMILES OCCNC(=O)c1cc(n[nH]1)-c1ccc(Cl)c(Cl)c1Cl

InChI Key InChIKey=NQORNRXANZIMLI-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50253982   

TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50253982(CHEMBL461194 | N-(2-hydroxyethyl)-3-(2,3,4-trichlo...)
Affinity DataIC50:  7.44nMAssay Description:Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (SBMRI, San Diego, CA) NIH Molecular Libraries Screen...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50253982(CHEMBL461194 | N-(2-hydroxyethyl)-3-(2,3,4-trichlo...)
Affinity DataIC50:  4.22nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGlyceraldehyde-3-phosphate dehydrogenase(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50253982(CHEMBL461194 | N-(2-hydroxyethyl)-3-(2,3,4-trichlo...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of GAPDH (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, placental type(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50253982(CHEMBL461194 | N-(2-hydroxyethyl)-3-(2,3,4-trichlo...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PLAP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50253982(CHEMBL461194 | N-(2-hydroxyethyl)-3-(2,3,4-trichlo...)
Affinity DataIC50:  5nMAssay Description:Inhibition of TNSALP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed