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BDBM50254318 (2,4-dihydrochromeno[4,3-c]pyrazol-3-yl)(pyrrolidin-1-yl)methanone::CHEMBL468052::cid_16654607

SMILES: O=C(N1CCCC1)c1[nH]nc-2c1COc1ccccc-21

InChI Key: InChIKey=NZRAHJBIECNCGM-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50254318   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Alkaline phosphatase placental-like


(Homo sapiens (Human))
BDBM50254318
PNG
((2,4-dihydrochromeno[4,3-c]pyrazol-3-yl)(pyrrolidi...)
Show SMILES O=C(N1CCCC1)c1[nH]nc-2c1COc1ccccc-21
Show InChI InChI=1S/C15H15N3O2/c19-15(18-7-3-4-8-18)14-11-9-20-12-6-2-1-5-10(12)13(11)16-17-14/h1-2,5-6H,3-4,7-9H2,(H,16,17)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PCBioAssay
n/an/a>1.00E+5n/an/an/an/an/an/a



Sanford-Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2JQ0ZDS
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Homo sapiens (Human))
BDBM50254318
PNG
((2,4-dihydrochromeno[4,3-c]pyrazol-3-yl)(pyrrolidi...)
Show SMILES O=C(N1CCCC1)c1[nH]nc-2c1COc1ccccc-21
Show InChI InChI=1S/C15H15N3O2/c19-15(18-7-3-4-8-18)14-11-9-20-12-6-2-1-5-10(12)13(11)16-17-14/h1-2,5-6H,3-4,7-9H2,(H,16,17)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 500n/an/an/an/an/an/a



Institute for Medical Research

Curated by ChEMBL


Assay Description
Inhibition of TNSALP (unknown origin)


Bioorg Med Chem Lett 19: 222-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.10.107
BindingDB Entry DOI: 10.7270/Q2CR5T64
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Homo sapiens (Human))
BDBM50254318
PNG
((2,4-dihydrochromeno[4,3-c]pyrazol-3-yl)(pyrrolidi...)
Show SMILES O=C(N1CCCC1)c1[nH]nc-2c1COc1ccccc-21
Show InChI InChI=1S/C15H15N3O2/c19-15(18-7-3-4-8-18)14-11-9-20-12-6-2-1-5-10(12)13(11)16-17-14/h1-2,5-6H,3-4,7-9H2,(H,16,17)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PCBioAssay
n/an/a 289n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (SBMRI, San Diego, CA) NIH Molecular Libraries Screen...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2CR5RRG
More data for this
Ligand-Target Pair