BDBM50254456 CHEMBL447392::N-(2-chlorobenzyl)-2-(N-(4-isobutoxy-3-methoxybenzyl)-4-((4-methylpiperazin-1-yl)methyl)phenylsulfonamido)acetamide
SMILES COc1cc(CN(CC(=O)NCc2ccccc2Cl)S(=O)(=O)c2ccc(CN3CCN(C)CC3)cc2)ccc1OCC(C)C
InChI Key InChIKey=APARDBNFWVLXJI-UHFFFAOYSA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50254456
TargetB1 bradykinin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Displacement of [3H]Lys0-des-Arg9-BK at human bradykinin B1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetB1 bradykinin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Displacement of [3H]desArg from human B1 in human WI 38 cellsMore data for this Ligand-Target Pair
TargetB1 bradykinin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 37nMAssay Description:Binding affinity to human bradykinin B1 receptorMore data for this Ligand-Target Pair
TargetB1 bradykinin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 37nMAssay Description:Antagonist activity at human cloned B1 receptor expressed in african green monkey COS7 cells by calcium mobilization assayMore data for this Ligand-Target Pair