BDBM50254774 CHEMBL277805

SMILES Nc1ccccc1NC(=O)CCCCCC(=O)Nc1ccccc1

InChI Key InChIKey=ZAIULUYKQLVQFH-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50254774   

TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
University of Reims Champagne

Curated by ChEMBL
LigandPNGBDBM50254774(CHEMBL277805)
Affinity DataIC50: 69nMAssay Description:Inhibition of human full length C-terminal His-tagged HDAC3/N-terminal GST-tagged human NCOR2 co-expressed in baculovirus infected Sf9 insect cells p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2019
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50254774(CHEMBL277805)
Affinity DataIC50: 69nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Reims Champagne

Curated by ChEMBL
LigandPNGBDBM50254774(CHEMBL277805)
Affinity DataIC50: 199nMAssay Description:Inhibition of human full length C-terminal His/FLAG-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells preincubated for 2 hrs followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2019
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Reims Champagne

Curated by ChEMBL
LigandPNGBDBM50254774(CHEMBL277805)
Affinity DataIC50: 199nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
University of Reims Champagne

Curated by ChEMBL
LigandPNGBDBM50254774(CHEMBL277805)
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of human full length C-terminal FLAG-tagged HDAC2 expressed in baculovirus infected Sf9 insect cells preincubated for 2 hrs followed by Fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2019
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
University of Reims Champagne

Curated by ChEMBL
LigandPNGBDBM50254774(CHEMBL277805)
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
University of Reims Champagne

Curated by ChEMBL
LigandPNGBDBM50254774(CHEMBL277805)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) preincubated for 2 hrs followed by Fluor-de-Lys substrate addition measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2019
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
University of Reims Champagne

Curated by ChEMBL
LigandPNGBDBM50254774(CHEMBL277805)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50254774(CHEMBL277805)
Affinity DataIC50: 7.80E+4nMAssay Description:Inhibition of HDAC in human HeLa cell extract by fluorescence plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
University of Reims Champagne

Curated by ChEMBL
LigandPNGBDBM50254774(CHEMBL277805)
Affinity DataIC50: 1.80E+5nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged HDAC7 expressed in baculovirus infected insect cells preincubated for 2 hrs followed by Fluor-d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2019
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
University of Reims Champagne

Curated by ChEMBL
LigandPNGBDBM50254774(CHEMBL277805)
Affinity DataIC50: 1.80E+5nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged/C-terminal His-tagged HDAC4 expressed in baculovirus infected insect cells preincubated for 2 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2019
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
University of Reims Champagne

Curated by ChEMBL
LigandPNGBDBM50254774(CHEMBL277805)
Affinity DataIC50: 1.80E+5nMAssay Description:Inhibition of human recombinant C-terminal His-tagged HDAC5 expressed in baculovirus infected insect cells preincubated for 2 hrs followed by Fluor-d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2019
Entry Details Article
PubMed