BDBM50254790 (S)-Norfluoxetine::CHEMBL465123::NORFLUOXETINE

SMILES: c1ccc(cc1)[C@H](CCN)Oc2ccc(cc2)C(F)(F)F

InChI Key: InChIKey=WIQRCHMSJFFONW-UHFFFAOYSA-N

Data: 37 KI  5 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 43 hits for monomerid = 50254790   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily C member 1 (Rat)	BDBM50254790 (NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50254790 (NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.29E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Human)	BDBM50254790 (NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.49E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Human)	BDBM50254790 (NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.81E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Human)	BDBM50254790 (NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 2 (Human)	BDBM50254790 (NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	9.00E+3	n/a	n/a	7.3	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Human)	BDBM50254790 (NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine) Show SMILES Show InChI	GoogleScholar	UniChem		1.47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rat)	BDBM50254790 (NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine) Show SMILES Show InChI	GoogleScholar	UniChem		1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Human)	BDBM50254790 (NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine) Show SMILES Show InChI	GoogleScholar	UniChem		2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rat)	BDBM50254790 (NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine) Show SMILES Show InChI	GoogleScholar	UniChem		3.15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rat)	BDBM50254790 (NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine) Show SMILES Show InChI	GoogleScholar	UniChem		3.15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rat)	BDBM50254790 (NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine) Show SMILES Show InChI	GoogleScholar	UniChem		13.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rat)	BDBM50254790 (NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine) Show SMILES Show InChI	GoogleScholar	UniChem		30.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Human)	BDBM50254790 (NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine) Show SMILES Show InChI	GoogleScholar	UniChem		50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Human)	BDBM50254790 (NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine) Show SMILES Show InChI	GoogleScholar	UniChem		54	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50254790 (NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine) Show SMILES Show InChI	GoogleScholar	UniChem		91.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rat)	BDBM50254790 (NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine) Show SMILES Show InChI	GoogleScholar	UniChem		117	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rat)	BDBM50254790 (NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine) Show SMILES Show InChI	GoogleScholar	UniChem		157	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rat)	BDBM50254790 (NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine) Show SMILES Show InChI	GoogleScholar	UniChem		286	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50254790 (NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine) Show SMILES Show InChI	GoogleScholar	UniChem		295	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Human)	BDBM50254790 (NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine) Show SMILES Show InChI	GoogleScholar	UniChem		420	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50254790 (NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine) Show SMILES Show InChI	GoogleScholar	UniChem		600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rat)	BDBM50254790 (NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine) Show SMILES Show InChI	GoogleScholar	UniChem		638	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Human)	BDBM50254790 (NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine) Show SMILES Show InChI	GoogleScholar	UniChem		760	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Human)	BDBM50254790 (NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine) Show SMILES Show InChI	GoogleScholar	UniChem		810	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rat)	BDBM50254790 (NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine) Show SMILES Show InChI	GoogleScholar	UniChem		1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Human)	BDBM50254790 (NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine) Show SMILES Show InChI	GoogleScholar	UniChem		1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Human)	BDBM50254790 (NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine) Show SMILES Show InChI	GoogleScholar	UniChem		1.43E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Human)	BDBM50254790 (NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine) Show SMILES Show InChI	GoogleScholar	UniChem		2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Human)	BDBM50254790 (NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine) Show SMILES Show InChI	GoogleScholar	UniChem		2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Human)	BDBM50254790 (NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine) Show SMILES Show InChI	GoogleScholar	UniChem		3.05E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Human)	BDBM50254790 (NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine) Show SMILES Show InChI	GoogleScholar	UniChem		3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Human)	BDBM50254790 (NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine) Show SMILES Show InChI	GoogleScholar	UniChem		3.95E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Human)	BDBM50254790 (NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine) Show SMILES Show InChI	GoogleScholar	UniChem		4.54E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Human)	BDBM50254790 (NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine) Show SMILES Show InChI	GoogleScholar	UniChem		4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Norepinephrine transporter (Rat)	BDBM50254790 (NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine) Show SMILES Show InChI	GoogleScholar	UniChem		5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Human)	BDBM50254790 (NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine) Show SMILES Show InChI	GoogleScholar	UniChem		5.06E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Human)	BDBM50254790 (NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine) Show SMILES Show InChI	GoogleScholar	UniChem		6.19E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H1 receptor (Human)	BDBM50254790 (NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM50254790 (NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Human)	BDBM50254790 (NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Human)	BDBM50254790 (NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Human)	BDBM50254790 (NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair