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BDBM50255145 4-(2-fluorophenylamino)-6,7-dimethoxyquinoline-3-carboxamide::CHEMBL442591

SMILES: COc1cc2ncc(C(N)=O)c(Nc3ccccc3F)c2cc1OC

InChI Key: InChIKey=UZANVGMPALOCQJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50255145   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM50255145
PNG
(4-(2-fluorophenylamino)-6,7-dimethoxyquinoline-3-c...)
Show SMILES COc1cc2ncc(C(N)=O)c(Nc3ccccc3F)c2cc1OC
Show InChI InChI=1S/C18H16FN3O3/c1-24-15-7-10-14(8-16(15)25-2)21-9-11(18(20)23)17(10)22-13-6-4-3-5-12(13)19/h3-9H,1-2H3,(H2,20,23)(H,21,22)
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 9n/an/an/an/an/an/a



AstraZeneca R&D Boston

Curated by ChEMBL


Assay Description
Inhibition of His-tagged CSF1R catalytic domain (unknown origin) expressed in baculovirus by HTRF assay


Bioorg Med Chem Lett 19: 697-700 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.046
BindingDB Entry DOI: 10.7270/Q26M36P8
More data for this
Ligand-Target Pair