BDBM50255145 4-(2-fluorophenylamino)-6,7-dimethoxyquinoline-3-carboxamide::CHEMBL442591

SMILES COc1cc2ncc(C(N)=O)c(Nc3ccccc3F)c2cc1OC

InChI Key InChIKey=UZANVGMPALOCQJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50255145   

TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255145(4-(2-fluorophenylamino)-6,7-dimethoxyquinoline-3-c...)
Affinity DataIC50:  9nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain (unknown origin) expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed