BDBM50255196 CHEMBL481816::N1-{(+/-)-4'-[(6''-amino-4''-methylpyridin-2''-yl)methyl]pyrrolidin-3'-yl}-N2-(3'-fluorophenethyl)-N1-methylethane-1,2-diamine

SMILES CN(CCNCCc1cccc(F)c1)[C@@H]1CNC[C@@H]1Cc1cc(C)cc(N)n1

InChI Key InChIKey=JVMWZAGTWUFHRM-GHTZIAJQSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50255196   

TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50255196(CHEMBL481816 | N1-{(+/-)-4'-[(6''-amino-4''-methyl...)
Affinity DataKi:  326nMAssay Description:Inhibition of rat recombinant nNOS expressed in Escherichia coli by hemoglobin capture assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50255196(CHEMBL481816 | N1-{(+/-)-4'-[(6''-amino-4''-methyl...)
Affinity DataKi:  3.82E+4nMAssay Description:Inhibition of mouse recombinant iNOS expressed in Escherichia coli by hemoglobin capture assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50255196(CHEMBL481816 | N1-{(+/-)-4'-[(6''-amino-4''-methyl...)
Affinity DataKi:  9.24E+4nMAssay Description:Inhibition of bovine recombinant eNOS expressed in Escherichia coli by hemoglobin capture assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed