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BDBM50255259 4-(3-chlorophenylamino)-6,7-dimethoxyquinoline-3-carboxamide::CHEMBL517544

SMILES: COc1cc2ncc(C(N)=O)c(Nc3cccc(Cl)c3)c2cc1OC

InChI Key: InChIKey=PDHPVHXEKOECNM-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50255259   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Macrophage colony stimulating factor receptor


(Homo sapiens (Human))
BDBM50255259
PNG
(4-(3-chlorophenylamino)-6,7-dimethoxyquinoline-3-c...)
Show SMILES COc1cc2ncc(C(N)=O)c(Nc3cccc(Cl)c3)c2cc1OC
Show InChI InChI=1S/C18H16ClN3O3/c1-24-15-7-12-14(8-16(15)25-2)21-9-13(18(20)23)17(12)22-11-5-3-4-10(19)6-11/h3-9H,1-2H3,(H2,20,23)(H,21,22)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 18n/an/an/an/an/an/a



AstraZeneca R&D Boston

Curated by ChEMBL


Assay Description
Inhibition of His-tagged CSF1R catalytic domain (unknown origin) expressed in baculovirus by HTRF assay


Bioorg Med Chem Lett 19: 697-700 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.046
BindingDB Entry DOI: 10.7270/Q26M36P8
More data for this
Ligand-Target Pair