BDBM50255473 2-((4-(3-(4-bromophenyl)benzo[d]isothiazol-6-yloxy)butyl)(ethyl)amino)ethanol hydrochloride::CHEMBL479464

SMILES CCN(CCO)CCCCOc1ccc2c(nsc2c1)-c1ccc(Br)cc1

InChI Key InChIKey=XHOKJNHLSGAYJL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50255473   

TargetLanosterol synthase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50255473(2-((4-(3-(4-bromophenyl)benzo[d]isothiazol-6-yloxy...)
Affinity DataIC50:  520nMAssay Description:Inhibition of human OSC expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50255473(2-((4-(3-(4-bromophenyl)benzo[d]isothiazol-6-yloxy...)
Affinity DataIC50:  17.8nMAssay Description:Inhibition of human liver microsome 2,3-OSC after 1 hr by Silica gel plate phosphor imagingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCycloartenol synthase(Arabidopsis thaliana)
Università

Curated by ChEMBL
LigandPNGBDBM50255473(2-((4-(3-(4-bromophenyl)benzo[d]isothiazol-6-yloxy...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of Arabidopsis thaliana cycloartenol synthase expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase ERG7(Saccharomyces cerevisiae)
Università

Curated by ChEMBL
LigandPNGBDBM50255473(2-((4-(3-(4-bromophenyl)benzo[d]isothiazol-6-yloxy...)
Affinity DataIC50:  700nMAssay Description:Inhibition of yeast OSC expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed