BDBM50255954 2-(1H-Indol-6-yl)-1-[1-(1-methylcyclooctyl)piperidin-4-yl]-1Hbenzimidazole::CHEMBL481548

SMILES CC1(CCCCCCC1)N1CCC(CC1)n1c(nc2ccccc12)-c1ccc2cc[nH]c2c1

InChI Key InChIKey=NPOOASADSCQJAU-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50255954   

TargetNociceptin receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255954(2-(1H-Indol-6-yl)-1-[1-(1-methylcyclooctyl)piperid...)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]N/OFQ from human NOP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255954(2-(1H-Indol-6-yl)-1-[1-(1-methylcyclooctyl)piperid...)
Affinity DataKi:  151nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255954(2-(1H-Indol-6-yl)-1-[1-(1-methylcyclooctyl)piperid...)
Affinity DataEC50:  8.63E+3nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHOK1 cells by [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255954(2-(1H-Indol-6-yl)-1-[1-(1-methylcyclooctyl)piperid...)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human NOP receptor expressed in HEK293 cells by [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed