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BDBM50256581 CHEMBL4078240

SMILES: CC(C(=O)NCc1ccc(nc1-c1ccc(F)cc1)C(C)(C)C)c1ccc(NS(C)(=O)=O)c(F)c1

InChI Key: InChIKey=AEQVLCITSYJZAZ-UHFFFAOYNA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50256581   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM50256581
PNG
(CHEMBL4078240)
Show SMILES CC(C(=O)NCc1ccc(nc1-c1ccc(F)cc1)C(C)(C)C)c1ccc(NS(C)(=O)=O)c(F)c1
Show InChI InChI=1/C26H29F2N3O3S/c1-16(18-8-12-22(21(28)14-18)31-35(5,33)34)25(32)29-15-19-9-13-23(26(2,3)4)30-24(19)17-6-10-20(27)11-7-17/h6-14,16,31H,15H2,1-5H3,(H,29,32)
PDB
MMDB

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KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
PubMed
0.300n/an/an/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Antagonist activity at human TRPV1 expressed in CHOK1 cells assessed as inhibition of capsaicin induced calcium influx pretreated for 6 mins followed...


Bioorg Med Chem 25: 2451-2462 (2017)

More data for this
Ligand-Target Pair