BDBM50256779 CHEMBL451232::trans-[2-(2-Chloro-4-fluorophenyl)cyclopropyl]methylamine Hydrochloride

SMILES NC[C@H]1C[C@@H]1c1ccc(F)cc1Cl

InChI Key InChIKey=ZKKSFFWCPNXRRU-MUWHJKNJSA-N

Data  6 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50256779   

Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50256779(CHEMBL451232 | trans-[2-(2-Chloro-4-fluorophenyl)c...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]LSD from human 5HT2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50256779(CHEMBL451232 | trans-[2-(2-Chloro-4-fluorophenyl)c...)
Affinity DataKi:  203nMAssay Description:Displacement of [3H]mesulergine from 5HT2C receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50256779(CHEMBL451232 | trans-[2-(2-Chloro-4-fluorophenyl)c...)
Affinity DataKi:  254nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50256779(CHEMBL451232 | trans-[2-(2-Chloro-4-fluorophenyl)c...)
Affinity DataKi:  1.04E+3nMAssay Description:Displacement of [3H]citalopram from SERT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50256779(CHEMBL451232 | trans-[2-(2-Chloro-4-fluorophenyl)c...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]nisoxetine from NET (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50256779(CHEMBL451232 | trans-[2-(2-Chloro-4-fluorophenyl)c...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]WIN35428 from DAT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50256779(CHEMBL451232 | trans-[2-(2-Chloro-4-fluorophenyl)c...)
Affinity DataEC50:  3nMAssay Description:Agonist activity at human 5HT2C receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50256779(CHEMBL451232 | trans-[2-(2-Chloro-4-fluorophenyl)c...)
Affinity DataEC50:  22nMAssay Description:Agonist activity at human 5HT2B receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50256779(CHEMBL451232 | trans-[2-(2-Chloro-4-fluorophenyl)c...)
Affinity DataEC50:  91nMAssay Description:Agonist activity at human 5HT2A receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed