BDBM50257077 CHEMBL515432::N1-(2-aminophenyl)-N4-(4-methyl-3-(4-(pyridin-3-yl)thiazol-2-ylamino)phenyl)terephthalamide

SMILES Cc1ccc(NC(=O)c2ccc(cc2)C(=O)Nc2ccccc2N)cc1Nc1ncc(s1)-c1cccnc1

InChI Key InChIKey=MMIKNEYLJPHVLH-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50257077   

TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50257077(CHEMBL515432 | N1-(2-aminophenyl)-N4-(4-methyl-3-(...)
Affinity DataIC50:  2.09E+4nMAssay Description:Inhibition of human recombinant HDAC6 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50257077(CHEMBL515432 | N1-(2-aminophenyl)-N4-(4-methyl-3-(...)
Affinity DataIC50:  4.60E+4nMAssay Description:Inhibition of VEGFR2 (unknown origin) by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50257077(CHEMBL515432 | N1-(2-aminophenyl)-N4-(4-methyl-3-(...)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of PDGFRbeta (unknown origin) by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50257077(CHEMBL515432 | N1-(2-aminophenyl)-N4-(4-methyl-3-(...)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of wild-type c-Abl (unknown origin) by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50257077(CHEMBL515432 | N1-(2-aminophenyl)-N4-(4-methyl-3-(...)
Affinity DataIC50:  170nMAssay Description:Inhibition of human recombinant HDAC1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed