BDBM50257341 CHEMBL4094447
SMILES Cn1c(CNc2cccc(c2)C(=O)NCc2ccccc2C(F)(F)F)nnc1-c1ccncn1
InChI Key InChIKey=DFYJVEZNHJSNLL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50257341
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human PKCalpha active using MBP as substrate after 60 mins in presence of [gamma-32]ATP by scintillation countingMore data for this Ligand-Target Pair
Affinity DataEC50: 7.40E+3nMAssay Description:Inhibition of human GRK2 expressed in HEK-B2 cells assessed as isoproterenol-stimulated cAMP accumulation preincubation for 20 mins followed by isopr...More data for this Ligand-Target Pair
Affinity DataIC50: 720nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ROCK2 catalytic domain (1 to 553 residues) expressed in baculovirus expression system using STK...More data for this Ligand-Target Pair
Affinity DataIC50: 7.80nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged GRK2 expressed in baculovirus expression system using ulight topo2alpha as substrate preincubat...More data for this Ligand-Target Pair