BDBM50257426 CHEMBL4077447
SMILES Clc1ccccc1CNC(=O)c1cccc(NCc2nnc([nH]2)-c2ccncc2)c1
InChI Key InChIKey=APIVUJRBRZKGIM-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50257426
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human PKCalpha active using MBP as substrate after 60 mins in presence of [gamma-32]ATP by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged GRK2 expressed in baculovirus expression system using ulight topo2alpha as substrate preincubat...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ROCK2 catalytic domain (1 to 553 residues) expressed in baculovirus expression system using STK...More data for this Ligand-Target Pair
Affinity DataEC50: 1.20E+5nMAssay Description:Inhibition of human GRK2 expressed in HEK-B2 cells assessed as isoproterenol-stimulated cAMP accumulation preincubation for 20 mins followed by isopr...More data for this Ligand-Target Pair