BDBM50257829 2-(4-amino-5-(5-iodo-2-isopropyl-4-methoxyphenoxy)pyrimidin-2-ylamino)propane-1,3-diol::CHEMBL494161::Ro-51

SMILES: COc1cc(C(C)C)c(Oc2cnc(NC(CO)CO)nc2N)cc1I

InChI Key: InChIKey=PAYROHWFGZADBR-UHFFFAOYSA-N

Data: 13 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50257829   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 3 (Human)	BDBM50257829 (Ro-51 | 2-(4-amino-5-(5-iodo-2-isopropyl-4-methoxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
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P2X purinoceptor 2/3 (Human)	BDBM50257829 (Ro-51 | 2-(4-amino-5-(5-iodo-2-isopropyl-4-methoxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
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P2X purinoceptor 1 (Human)	BDBM50257829 (Ro-51 | 2-(4-amino-5-(5-iodo-2-isopropyl-4-methoxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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P2X purinoceptor 2 (Human)	BDBM50257829 (Ro-51 | 2-(4-amino-5-(5-iodo-2-isopropyl-4-methoxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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P2X purinoceptor 4 (Human)	BDBM50257829 (Ro-51 | 2-(4-amino-5-(5-iodo-2-isopropyl-4-methoxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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P2X purinoceptor 7 (Human)	BDBM50257829 (Ro-51 | 2-(4-amino-5-(5-iodo-2-isopropyl-4-methoxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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P2X purinoceptor 2 (Human)	BDBM50257829 (Ro-51 | 2-(4-amino-5-(5-iodo-2-isopropyl-4-methoxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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P2X purinoceptor 7 (Human)	BDBM50257829 (Ro-51 | 2-(4-amino-5-(5-iodo-2-isopropyl-4-methoxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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P2X purinoceptor 1 (Human)	BDBM50257829 (Ro-51 | 2-(4-amino-5-(5-iodo-2-isopropyl-4-methoxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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P2X purinoceptor 4 (Human)	BDBM50257829 (Ro-51 | 2-(4-amino-5-(5-iodo-2-isopropyl-4-methoxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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P2X purinoceptor 5 (Human)	BDBM50257829 (Ro-51 | 2-(4-amino-5-(5-iodo-2-isopropyl-4-methoxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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P2X purinoceptor 2 (Human)	BDBM50257829 (Ro-51 | 2-(4-amino-5-(5-iodo-2-isopropyl-4-methoxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
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P2X purinoceptor 3 (Rat)	BDBM50257829 (Ro-51 | 2-(4-amino-5-(5-iodo-2-isopropyl-4-methoxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
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