BindingDB PrimarySearch_ki

Search and Browse
- Target
- Compound
- Special tools
- Citation
- Special Data Sets
- Other Databases
  - PDB 85% 100% Seq ID
  - UniProtKB/Swiss-Prot
  - UniProtKB/TrEMBL
  - PubMed
Download
- All Compounds & Data
- Target Names &
  - Ki IC50 Kd EC50
  - ΔG° ΔH° -TΔS°
Enter Data

BDBM50257891 6-(6-chloropyridin-3-yl)-1,6-diazaspiro[3.4]octane::CHEMBL492593

SMILES: Clc1ccc(cn1)N1CCC2(CCN2)C1

InChI Key: InChIKey=JGNWYPPUUWHRGM-UHFFFAOYSA-N

Data: 1 KI 2 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50257891
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-4 (Human)	BDBM50257891 (6-(6-chloropyridin-3-yl)-1,6-diazaspiro[3.4]octane...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3 (Human)	BDBM50257891 (6-(6-chloropyridin-3-yl)-1,6-diazaspiro[3.4]octane...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	6.90E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Rat)	BDBM50257891 (6-(6-chloropyridin-3-yl)-1,6-diazaspiro[3.4]octane...) Show SMILES Show InChI	GoogleScholar	UniChem		21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair