BDBM50258182 (S)-N-(1-(4-(5-Chloro-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)propan-2-yl)-2-naphthamide, 69::(S)-N-(1-(4-(5-chloro-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)propan-2-yl)-2-naphthamide::(S)-N-(1-(4-(5-chloro-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)propan-2-yl)naphthalene-2-carboxamide::CHEMBL492572

SMILES C[C@@H](CN1CCC(CC1)n1c2ccc(Cl)cc2[nH]c1=O)NC(=O)c1ccc2ccccc2c1

InChI Key InChIKey=DRIMIUYGTDAQOX-KRWDZBQOSA-N

Data  7 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50258182   

TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM50258182((S)-N-(1-(4-(5-Chloro-2-oxo-2,3-dihydro-1H-benzo[d...)
Affinity DataIC50:  46nMT: 2°CAssay Description:PLD in vitro enzymatic assay using phospholipase D1(PLD1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM50258182((S)-N-(1-(4-(5-Chloro-2-oxo-2,3-dihydro-1H-benzo[d...)
Affinity DataIC50:  933nMT: 2°CAssay Description:PLD in vitro enzymatic assay using phospholipase D2(PLD2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM50258182((S)-N-(1-(4-(5-Chloro-2-oxo-2,3-dihydro-1H-benzo[d...)
Affinity DataIC50:  331nMT: 2°CAssay Description:Phopholipase D1(PLD)enzymatic inhibition assay using PLD1.d311More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM50258182((S)-N-(1-(4-(5-Chloro-2-oxo-2,3-dihydro-1H-benzo[d...)
Affinity DataEC50:  11nMT: 2°CAssay Description:cell-based assay using human non-small-cell lung cancer cell line, Calu-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50258182((S)-N-(1-(4-(5-Chloro-2-oxo-2,3-dihydro-1H-benzo[d...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of human GST-tagged PLD2A in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM50258182((S)-N-(1-(4-(5-Chloro-2-oxo-2,3-dihydro-1H-benzo[d...)
Affinity DataIC50:  46nMAssay Description:Inhibition of human PLD1 in Calu1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50258182((S)-N-(1-(4-(5-Chloro-2-oxo-2,3-dihydro-1H-benzo[d...)
Affinity DataIC50:  933nMAssay Description:Inhibition of GFP-labelled human PLD2 HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM50258182((S)-N-(1-(4-(5-Chloro-2-oxo-2,3-dihydro-1H-benzo[d...)
Affinity DataIC50:  11nMAssay Description:Inhibition of PLD1 in human calu1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM50258182((S)-N-(1-(4-(5-Chloro-2-oxo-2,3-dihydro-1H-benzo[d...)
Affinity DataEC50:  1.80E+3nMT: 2°CAssay Description:cell-based assay using HEK293-gfpPLD2 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed