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BDBM50258444 3-(5-tert-Butyl-2,3-dihydrobenzofuran-7-yl)-N-(3-fluoro-4-(methylsulfonamido)benzyl)propanamide::CHEMBL512459

SMILES: CC(C)(C)c1cc2CCOc2c(CCC(=O)NCc2ccc(NS(C)(=O)=O)c(F)c2)c1

InChI Key: InChIKey=KKWWWMAVXUWRKR-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50258444   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vanilloid receptor


(Rattus norvegicus (rat))
BDBM50258444
PNG
(3-(5-tert-Butyl-2,3-dihydrobenzofuran-7-yl)-N-(3-f...)
Show SMILES CC(C)(C)c1cc2CCOc2c(CCC(=O)NCc2ccc(NS(C)(=O)=O)c(F)c2)c1
Show InChI InChI=1S/C23H29FN2O4S/c1-23(2,3)18-12-16(22-17(13-18)9-10-30-22)6-8-21(27)25-14-15-5-7-20(19(24)11-15)26-31(4,28)29/h5,7,11-13,26H,6,8-10,14H2,1-4H3,(H,25,27)
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MMDB

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PC sid
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Similars

Article
PubMed
n/an/a 5.00E+3n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Antagonist activity at TRPV1 in Sprague-Dawley rat DRG neuron assessed as reduction of capsaicin-stimulated 45Ca2+ uptake


Bioorg Med Chem 17: 3557-67 (2009)


Article DOI: 10.1016/j.bmc.2009.04.010
BindingDB Entry DOI: 10.7270/Q2V124QJ
More data for this
Ligand-Target Pair