BDBM50258510 8-(4-tert-butylbenzoyl)-3-(2-oxo-2-(piperidin-1-yl)ethyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL468523

SMILES: CC(C)(C)c1ccc(cc1)C(=O)N1CCC2(CC1)N(CN(CC(=O)N1CCCCC1)C2=O)c1ccccc1

InChI Key: InChIKey=BNIJUNMGPGDSQV-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50258510   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NPC1-like intracellular cholesterol transporter 1 (Human)	BDBM50258510 (8-(4-tert-butylbenzoyl)-3-(2-oxo-2-(piperidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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NPC1-like intracellular cholesterol transporter 1 (Human)	BDBM50258510 (8-(4-tert-butylbenzoyl)-3-(2-oxo-2-(piperidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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NPC1-like intracellular cholesterol transporter 1 (Rat)	BDBM50258510 (8-(4-tert-butylbenzoyl)-3-(2-oxo-2-(piperidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Niemann-Pick C1-like 1 protein (Dog)	BDBM50258510 (8-(4-tert-butylbenzoyl)-3-(2-oxo-2-(piperidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Niemann-Pick C1-like 1 protein (Rhesus macaque)	BDBM50258510 (8-(4-tert-butylbenzoyl)-3-(2-oxo-2-(piperidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NPC1-like intracellular cholesterol transporter 1 (Human)	BDBM50258510 (8-(4-tert-butylbenzoyl)-3-(2-oxo-2-(piperidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair